Kainicacid(Cat.No.0222)cagedwiththephotosensitive4-methoxy-7-nitroindolinylgroup.GenerateslargeinwardcurrentsatrestingmembranepotentialuponwidefieldphotolysisinPurkinjeneurons.SelectivelyphotoactivateskainatereceptorswhenusedinconjunctionwithanAMPAantagoNIST,suchasGYKI53655(Cat.No.2555).Suitableforuncagingwith300-380nmexcitation.Exhibitsrapiduncagingraterelativetoionotropicglutamatereceptoractivation.Alsosuitablefortwo-photonuncagingexperimentsat720nm.
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M.Wt | 389.4 |
Formula | C19H23N3O6 |
Storage | Storeat-20°C |
Purity | ≥99%(HPLC) |
CASNumber | 1315378-75-6 |
PubChemID | 57414719 |
InChIKey | IQGCUMUIYXHZOT-AHIWAGSCSA-N |
Smiles | C=[C@@](C)[C@@H]1[C@H](CC(N2C(C([N+]([O-])=O)=CC=C3OC)=C3CC2)=O)[C@@H]([C@](O)=O)NC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 38.94 | 100 | |
water | 1.95 | 5mMwithgentlewarming |
Thefollowingdataisbasedontheproductmolecularweight389.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.57mL | 12.84mL | 25.68mL |
5mM | 0.51mL | 2.57mL | 5.14mL |
10mM | 0.26mL | 1.28mL | 2.57mL |
50mM | 0.05mL | 0.26mL | 0.51mL |