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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ML 179/4957/10/10 mg
产品编号:4957/10
市  场 价:¥3900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$195.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ML 179/4957/10/10 mg
商品介绍
Description:Selectiveliverreceptorhomolog1(LRH1)inverseagoNIST
ChemicalName:3-Cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveliverreceptorhomolog1(LRH1,NR5A2)inverseagonist(IC50=320nMandmaximumefficacyof64%repression).Exhibits>31-foldselectivityoverSF1.

CompoundLibraries

ML179isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt422.44
FormulaC21H25F3N4O2
StorageStoreat+4°C
Purity≥99%(HPLC)
PubChemID45100448
InChIKeyMFABFKUNLDYKGH-UHFFFAOYSA-N
SmilesO=C(C=C(N3CCN(C4=CC=CC(C(F)(F)F)=C4)CC3)NC2=O)N2C1CCCCC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO21.1250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight422.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.37mL11.84mL23.67mL
5mM0.47mL2.37mL4.73mL
10mM0.24mL1.18mL2.37mL
50mM0.05mL0.24mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet