请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/MKT 077/4621/10/10 mg
产品编号:4621/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 蛋白类>天然蛋白>白蛋白>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/MKT 077/4621/10/10 mg
商品介绍
Description:Bindsmot-2;selectivelycytotoxicincancercells
ChemicalName:1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-pyridiniumchloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Occupiesmortalin-2(mot-2),amemberoftheHsp70family,atitsp53bindingsiteandenablesp53translocationtothenucleus.Selectivelycytotoxic;causesgrowtharrestofcancercellsinculture.Alsoinhibitstelomeraseactivityandcross-linksF-actin.

CompoundLibraries

MKT077isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt432
FormulaC21H22ClN3OS2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber147366-41-4
PubChemID3037933
InChIKeyVSKYOTRJSLYFHX-UXJRWBAGSA-M
SmilesCN(C1=CC=CC=C1S2)/C2=C4/C(N(CC)/C(S4)=CC3=CC=CC=[N+]3CC)=O.[Cl-]

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO21.650
water21.650

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight432.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.31mL11.57mL23.15mL
5mM0.46mL2.31mL4.63mL
10mM0.23mL1.16mL2.31mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet