请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/MK 571/2338/10/10 mg
产品编号:2338/10
市  场 价:¥3500.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$175.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/MK 571/2338/10/10 mg
商品介绍
Description:PotentCysLT1(LTD4)inverseagoNIST.AlsoMRP1inhibitor
AlternativeNames:L-660711
ChemicalName:3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoicacid
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentCysLT1(LTD4)leukotrienereceptorinverseagonist(EC50=1.3nM).AntagonizesLTD4-inducedcontractionsofguineapigtracheaandileum(pA2valuesare9.4and10.5respectively).Alsoinhibitorofmultidrugresistanceprotein-1(MRP1)mediatedtransport;invitroaugmentstheeffectsofcytotoxicagentsonmalignantcells.

TechnicalData

M.Wt515.09
FormulaC26H27ClN2O3S2
StorageStoreat-20°C
CASNumber115104-28-4
PubChemID5281888
InChIKeyAXUZQJFHDNNPFG-UXBLZVDNSA-N
SmilesClC1=CC=C(C=CC(/C=C/C3=CC(C(SCCC(O)=O)SCCC(N(C)C)=O)=CC=C3)=N2)C2=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO51.51100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight515.09.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.94mL9.71mL19.41mL
5mM0.39mL1.94mL3.88mL
10mM0.19mL0.97mL1.94mL
50mM0.04mL0.19mL0.39mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet