请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/MK 1903/4622/50/50 mg
产品编号:4622/50
市  场 价:¥16500.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$825.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/MK 1903/4622/50/50 mg
商品介绍
Description:PotentandselectiveGPR109A(HCA2)agoNIST
ChemicalName:(4aR,5aR)-4,4a,5,5a-Tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2]pyrazole-3-carboxylicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivehydroxycarboxylicacidreceptor2(HCA2,GPR109A)fullagonist;exhibitsgreaterpotencythanniacininawholecellHTRF-cAMPassay(EC50valuesare12.9and51nMrespectively).ExhibitsnobindingattheGRP109Breceptor.

TechnicalData

M.Wt164.16
FormulaC8H8N2O2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1268882-43-4
PubChemID49763030
InChIKeyCUTZNERBKDMLAP-QWWZWVQMSA-N
Smiles[H][C@@]12CC3=C(NN=C3C(O)=O)[C@@]([H])1C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO16.42100
ethanol8.2150

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight164.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM6.09mL30.46mL60.92mL
5mM1.22mL6.09mL12.18mL
10mM0.61mL3.05mL6.09mL
50mM0.12mL0.61mL1.22mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet