Potentandselectivehydroxycarboxylicacidreceptor2(HCA2,GPR109A)fullagonist;exhibitsgreaterpotencythanniacininawholecellHTRF-cAMPassay(EC50valuesare12.9and51nMrespectively).ExhibitsnobindingattheGRP109Breceptor.
| M.Wt | 164.16 |
| Formula | C8H8N2O2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1268882-43-4 |
| PubChemID | 49763030 |
| InChIKey | CUTZNERBKDMLAP-QWWZWVQMSA-N |
| Smiles | [H][C@@]12CC3=C(NN=C3C(O)=O)[C@@]([H])1C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 16.42 | 100 | |
| ethanol | 8.21 | 50 |
Thefollowingdataisbasedontheproductmolecularweight164.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 6.09mL | 30.46mL | 60.92mL |
| 5mM | 1.22mL | 6.09mL | 12.18mL |
| 10mM | 0.61mL | 3.05mL | 6.09mL |
| 50mM | 0.12mL | 0.61mL | 1.22mL |



