Oxazolidinoneantibiotic.Inhibitsbacterialproteinsynthesispriortochaininitiation.Displayspotentantibacterialactivityagainstavarietyofmultidrug-resistantgram-positivemicrobesinvitroandinvivo.
SoldforresearchpurposesunderagreementfromPfizerInc.
LinezolidisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 337.35 |
| Formula | C16H20FN3O4 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 165800-03-3 |
| PubChemID | 441401 |
| InChIKey | TYZROVQLWOKYKF-ZDUSSCGKSA-N |
| Smiles | FC1=CC(N3C[C@H](CNC(C)=O)OC3=O)=CC=C1N2CCOCC2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.74 | 100 | |
| ethanol | 8.43 | 25 |
Thefollowingdataisbasedontheproductmolecularweight337.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.96mL | 14.82mL | 29.64mL |
| 5mM | 0.59mL | 2.96mL | 5.93mL |
| 10mM | 0.3mL | 1.48mL | 2.96mL |
| 50mM | 0.06mL | 0.3mL | 0.59mL |



