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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Lin28 1632/6068/10/10 mg
产品编号:6068/10
市  场 价:¥2980.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$149.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Lin28 1632/6068/10/10 mg
商品介绍
Description:RNAbindingproteinLin28inhibitor;promotesmESCdifferentiation;alsobromodomaininhibitor
ChemicalName:N-Methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

RNAbindingproteinLin28inhibitor(IC50=8μM).BlocksbindingofLin28tolet-7pre-microRNA.InhibitsstemnessandinducesdifferentiationofmurineESCs.Inhibitsgrowthoftumorcelllinesandtumor-sphereformationinvitro.Alsobromodomaininhibitor.

TechnicalData

M.Wt281.31
FormulaC15H15N5O
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber108825-65-6
PubChemID2737312
InChIKeyWPAQLESUVYGUJZ-UHFFFAOYSA-N
SmilesCN(C1=CC=CC(C2=NN3C(C)=NN=C3C=C2)=C1)C(C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.13100
ethanol28.13100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight281.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.55mL17.77mL35.55mL
5mM0.71mL3.55mL7.11mL
10mM0.36mL1.78mL3.55mL
50mM0.07mL0.36mL0.71mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet