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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Letrozole/4382/10/10 mg
产品编号:4382/10
市  场 价:¥1380.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$69.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Letrozole/4382/10/10 mg
商品介绍
Description:Potent,reversIBLenon-steroidalaromataseinhibitor
AlternativeNames:CGS20267
ChemicalName:4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,reversiblenon-steroidalaromataseinhibitor(IC50=11.5nM).Displaysantitumoreffectsinseveralanimalmodels.Suppressestheendogenousaromatase-inducedproliferationofMCF-7cells.

CompoundLibraries

LetrozoleisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt285.3
FormulaC17H11N5
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber112809-51-5
PubChemID3902
InChIKeyHPJKCIUCZWXJDR-UHFFFAOYSA-N
SmilesN#CC(C=C2)=CC=C2C(N3N=CN=C3)C1=CC=C(C#N)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.53100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight285.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.51mL17.53mL35.05mL
5mM0.7mL3.51mL7.01mL
10mM0.35mL1.75mL3.51mL
50mM0.07mL0.35mL0.7mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet