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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/β-Lapachone/1293/10/10 mg
产品编号:1293/10
市  场 价:¥2180.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$109.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/β-Lapachone/1293/10/10 mg
商品介绍
Description:DNAtopoisomeraseIinhibitor
ChemicalName:3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

DNAtopoisomeraseIinhibitor.Exhibitsadifferentinhibitorymechanismtocamptothecin(Cat.No.1100).Inducesapoptosisinavarietyofcelllines,includingprostatecancerandpromyelocyticleukemiacells;blocksthecellcycleinG0/G1.AlsohaseffectsonDNAtopoisomeraseII,NF-κB,AP-1,andJNK.

TechnicalData

M.Wt242.27
FormulaC15H14O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber4707-32-8
PubChemID3885
InChIKeyQZPQTZZNNJUOLS-UHFFFAOYSA-N
SmilesO=C(C(C3=C2OC(C)(C)CC3)=O)C1=C2C=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO24.23100
ethanol12.1150

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight242.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.13mL20.64mL41.28mL
5mM0.83mL4.13mL8.26mL
10mM0.41mL2.06mL4.13mL
50mM0.08mL0.41mL0.83mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet