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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/LY 255283/2208/10/10 mg
产品编号:2208/10
市  场 价:¥3500.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$175.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/LY 255283/2208/10/10 mg
商品介绍
Description:Selective,competitiveBLT2receptorantagoNIST
ChemicalName:1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selective,competitiveantagonistofBLT2receptors(IC50valuesare~1and>10μMathumanrecombinantBLT2andBLT1receptorsrespectively).InhibitsLTB4-inducedcontractionoflungparenchyma(pA2=7.2),andreducesLTB4-mediatedairwayobstructioninguineapigsfollowingi.v.andoraladministration. .

CompoundLibraries

LY255283isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt360.46
FormulaC19H28N4O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber117690-79-6
PubChemID122023
InChIKeyWCGXJPFHTHQNJL-UHFFFAOYSA-N
SmilesCCC1=C(OCCCCCC(C)(C)C2=NN=NN2)C=C(O)C(=C1)C(C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO36.05100
ethanol9.0125

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight360.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.77mL13.87mL27.74mL
5mM0.55mL2.77mL5.55mL
10mM0.28mL1.39mL2.77mL
50mM0.06mL0.28mL0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet