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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/LOE 908 hydrochloride/2314/10/10 mg
产品编号:2314/10
市  场 价:¥3180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$159.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/LOE 908 hydrochloride/2314/10/10 mg
商品介绍
Description:Broadspectrumcationchannelblocker;neuroprotective
ChemicalName:3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Broadspectrumcationchannelblocker.Inhibitsseveralcationchannelsincludingstore-operatedcalciumchannels(SOCs),voltage-operatedcalciumchannels(VOCs),non-selectivecationchannels(NSCCs),AMPA,NMDA,Na+andK+channels.Neuroprotective;reducescorticalinfarctsizeandimprovesneurologicaloutcomefollowingmiddlecerebralarteryocclusion.

TechnicalData

M.Wt749.29
FormulaC41H48N2O9.HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber143482-60-4
PubChemID56846451
InChIKeyUDKSNBMNKLDHNK-UHFFFAOYSA-N
SmilesCl.COC1=CC=C(CCN(CCC2=C(OC)C(OC)=C(OC)C=C2)C(=O)C(C2=CC=CC=C2)C2=NCCC3=CC(OC)=C(OC)C=C23)C(OC)=C1OC

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO74.93100
water37.4650

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight749.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.33mL6.67mL13.35mL
5mM0.27mL1.33mL2.67mL
10mM0.13mL0.67mL1.33mL
50mM0.03mL0.13mL0.27mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet