PotentandhighlyselectivecompetitivetachykininNK1receptorantagonist(IC50=2.3nM).
SoldwiththepermissionofMerckSharpandDohmeLtd.
L-732,138isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 472.39 |
Formula | C22H18F6N2O3 |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 148451-96-1 |
PubChemID | 44396853 |
InChIKey | BYYQYXVAWXAYQC-LJQANCHMSA-N |
Smiles | O=C(N[C@@](CC2=CNC3=C2C=CC=C3)([H])C(OCC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)=O)C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
ethanol | 47.24 | 100 |
Thefollowingdataisbasedontheproductmolecularweight472.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.12mL | 10.58mL | 21.17mL |
5mM | 0.42mL | 2.12mL | 4.23mL |
10mM | 0.21mL | 1.06mL | 2.12mL |
50mM | 0.04mL | 0.21mL | 0.42mL |