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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Kaempferol/3603/50/50 mg
产品编号:3603/50
市  场 价:¥1900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$95.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Kaempferol/3603/50/50 mg
商品介绍
Description:Proapoptotic;downregulatesPLK1expressionandactivatesmitochondrialCa2+uniporter
AlternativeNames:Kempferol
ChemicalName:3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

NaturallyoccurringflavonoidfoundinGingkobilobaandredwinesthatactivatesthemitochondrialCa2+uniporter(EC50=7μM).Inducescaspase-9-mediatedapoptosisinavarietyofcancercelllinesviadownregulationofpolo-likekinase1(PLK1)expression.Exhibitsantioxidantactivityandattenuatesosteoclasticbonereabsorptioninvitro.AlsoblocksEGF-inducedhistoneH3Ser10phosphorylationinmouseepidermalJB6C141cells.

CompoundLibraries

KaempferolisalsoofferedaspartoftheTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt286.24
FormulaC15H10O6
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber520-18-3
PubChemID5280863
InChIKeyIYRMWMYZSQPJKC-UHFFFAOYSA-N
SmilesO=C2C1=C(O)C=C(O)C=C1OC(C3=CC=C(O)C=C3)=C2O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.62100
ethanol28.62100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight286.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.49mL17.47mL34.94mL
5mM0.7mL3.49mL6.99mL
10mM0.35mL1.75mL3.49mL
50mM0.07mL0.35mL0.7mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet