PromotesdifferentiationofhumanESCsandiPSCsintocardiomyocyteswhenusedafterdaythreeinculture;differentiationefficiencyincreaseswhenusedafterinitialculturewithCHIR99021(Cat.No.4423).InducesdownregulationofWntsignalingtargetgenes;inhibitscanonicalWntsignalinginamannerdistinctfromotherknownWntinhibitors.
KY02111isalsoofferedaspartoftheTocriscreenPlusandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 376.86 |
Formula | C18H17ClN2O3S |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 1118807-13-8 |
PubChemID | 8582409 |
InChIKey | LXFKEVQQSKQXPR-UHFFFAOYSA-N |
Smiles | O=C(CCC3=CC=C(OC)C(OC)=C3)NC2=NC1=CC=C(Cl)C=C1S2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 18.84 | 50 |
Thefollowingdataisbasedontheproductmolecularweight376.86.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.65mL | 13.27mL | 26.54mL |
5mM | 0.53mL | 2.65mL | 5.31mL |
10mM | 0.27mL | 1.33mL | 2.65mL |
50mM | 0.05mL | 0.27mL | 0.53mL |