Antagonistoftheatypicalimidazolinebindingsite(putativeI3receptor)ofpancreaticβ-cells.Selectivelyblocksefaroxan-inducedinsulinsecretioninvitroandinvivo.
KU14RisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 214.27 |
Formula | C13H14N2O |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 189224-48-4 |
PubChemID | 4302964 |
InChIKey | JCWVNNMJXQJVNC-UHFFFAOYSA-N |
Smiles | CCC1(CC2=CC=CC=C2O1)C1=NC=CN1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 21.43 | 100 |
Thefollowingdataisbasedontheproductmolecularweight214.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 4.67mL | 23.34mL | 46.67mL |
5mM | 0.93mL | 4.67mL | 9.33mL |
10mM | 0.47mL | 2.33mL | 4.67mL |
50mM | 0.09mL | 0.47mL | 0.93mL |