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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/KRIBB11/5480/50/50 mg
产品编号:5480/50
市  场 价:¥8380.00
场      地:美国(厂家直采)
产品分类: 蛋白类>天然蛋白>白蛋白>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$419.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/KRIBB11/5480/50/50 mg
商品介绍
Description:HSF1inhibitor
ChemicalName:N2-1H-Indazol-5-yl-N6-methyl-3-nitro-2,6-pyridinediamine
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Heatshockfactor(HSF)inhibitor(IC50=1.2μM).IncreasesapoptosisincancercellstreatedwiththeHSP90inhibitorsGeldanamycin(Cat.No.1368)and17-AAG(Cat.No.1515).BlocksdownstreaminductionofHSP27andHSP70.Inhibitstumorgrowthinvivo.

TechnicalData

M.Wt284.27
FormulaC13H12N6O2
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber342639-96-7
PubChemID69894253
InChIKeyNDJJEQIMIJJCLL-UHFFFAOYSA-N
SmilesCNC1=NC(NC2=CC=C(NN=C3)C3=C2)=C([N+]([O-])=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.43100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight284.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.52mL17.59mL35.18mL
5mM0.7mL3.52mL7.04mL
10mM0.35mL1.76mL3.52mL
50mM0.07mL0.35mL0.7mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet