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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/KM 11060/3143/50/50 mg
产品编号:3143/50
市  场 价:¥12580.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$629.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/KM 11060/3143/50/50 mg
商品介绍
Description:CorrectsF508del-CFTRtrafficking
ChemicalName:7-Chloro-4-[4-[4-chlorophenyl)sulfonyl]-1-piperazinyl]quinoline
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CorrectsF508del-CFTRtrafficking;increasestheamountoffunctionalCFTRattheplasmamembrane(~75%).ShowntoinhibitPDE5activity.

TechnicalData

M.Wt422.33
FormulaC19H17Cl2N3O2S
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber774549-97-2
PubChemID1241327
InChIKeyGIEHIZKCIZLXLF-UHFFFAOYSA-N
SmilesClC(C=C4)=CC=C4S(N(CC3)CCN3C1=CC=NC2=C1C=CC(Cl)=C2)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO42.23100
ethanol4.2210

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight422.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.37mL11.84mL23.68mL
5mM0.47mL2.37mL4.74mL
10mM0.24mL1.18mL2.37mL
50mM0.05mL0.24mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet