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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/KH 7/3834/10/10 mg
产品编号:3834/10
市  场 价:¥3180.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$159.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/KH 7/3834/10/10 mg
商品介绍
Description:Selectivesolubleadenylylcyclaseinhibitor
ChemicalName:(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivesolubleadenylylcyclase(sAC)inhibitor(IC50=3-10μMinvivo).Inerttowardstransmembraneadenylylcyclase(tmAC)invitroandinwholecellsatconcentrationsupto300μM.BlockssynthesisofcAMPanddisplaysanantiapoptoticeffectatconcentrationsof1-100μM.

TechnicalData

M.Wt419.3
FormulaC17H15BrN4O2S
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber330676-02-3
PubChemID6843191
InChIKeyGEHVZUUHMWNMAY-UHFFFAOYSA-N
SmilesOC(C=CC(Br)=C2)=C2/C=N/NC(C(C)SC1=NC(C=CC=C3)=C3N1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO41.93100
ethanol10.4825

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight419.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.38mL11.92mL23.85mL
5mM0.48mL2.38mL4.77mL
10mM0.24mL1.19mL2.38mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet