SelectiveinhibitorofP-selectin-mediatedcelladhesion(IC50=1.97μM)thatdisplaysnoeffectsonL-selectin-andE-selectin-mediatedadhesion.BlocksP-selectin-mediatedbindinginvitroandleukocyteaccumulationinvivo.
KF38789isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 375.44 |
Formula | C19H21NO5S |
Storage | Desiccateat+4°C |
Purity | ≥97%(HPLC) |
CASNumber | 257292-29-8 |
PubChemID | 5373277 |
InChIKey | FJDFKOSFDPIMBV-NBVRZTHBSA-N |
Smiles | COC1=CC=C(C2CC(=NCCS2)C2=C(O)C=C(C)OC2=O)C(OC)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 37.54 | 100 |
Thefollowingdataisbasedontheproductmolecularweight375.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.66mL | 13.32mL | 26.64mL |
5mM | 0.53mL | 2.66mL | 5.33mL |
10mM | 0.27mL | 1.33mL | 2.66mL |
50mM | 0.05mL | 0.27mL | 0.53mL |