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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/KB-R7943 mesylate/1244/50/50 mg
产品编号:1244/50
市  场 价:¥13300.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$665.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/KB-R7943 mesylate/1244/50/50 mg
商品介绍
Description:Na+/Ca2+exchangeinhibitor(reversemode)
ChemicalName:2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothioureamesylate
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectiveinhibitorofthereversemodeoftheNa+/Ca2+exchanger(IC50=0.7μM).AlsoinhibitsthemitochondrialCa2+uniporter(MCU;IC50=5.5μM).DoesnotaffectNa+-dependenttransportsystemsorionotropicglutamatereceptors.

CompoundLibraries

KB-R7943mesylateisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt427.49
FormulaC16H17N3O3S.CH3SO3H
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber182004-65-5
PubChemID9823846
InChIKeyWGIKEBHIKKWJLG-UHFFFAOYSA-N
SmilesCS(O)(=O)=O.NC(=N)SCCC1=CC=C(OCC2=CC=C(C=C2)[N+]([O-])=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO42.75100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight427.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.34mL11.7mL23.39mL
5mM0.47mL2.34mL4.68mL
10mM0.23mL1.17mL2.34mL
50mM0.05mL0.23mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet