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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Jasplakinolide/2792/100U/100 ug
产品编号:2792/100U
市  场 价:¥6180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$309.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Jasplakinolide/2792/100U/100 ug
商品介绍
Description:StABIlizesF-actin;promotesactinpolymerization
ChemicalName:Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl]
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Rapidlystabilizespre-formedactinfilamentsandinhibitstheirdisassemblyinvitro.AlsoinducespolymerizationofactinmonomersintoF-actininvivo.ShowntobindtoF-actincompetitivelywithphalloidin(Cat.No.4535)(Kd~15nM).Exhibitsantifungalandantiproliferativeeffects(IC50=35nMforantiproliferativeactivityinPC3cells).Cellpermeable.

TechnicalData

M.Wt709.67
FormulaC36H45BrN4O6
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber102396-24-7
PubChemID9831636
InChIKeyGQWYWHOHRVVHAP-DHKPLNAMSA-N
SmilesC[C@H](C[C@H](C)OC1=O)/C=C(C)/C[C@H](C)C(N[C@H](C(N([C@H](CC2=C(Br)NC3=C2C=CC=C3)C(N[C@@H]([C@]4=CC=C(O)C=C4)C1)=O)C)=O)C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO23

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight709.67.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.41mL7.05mL14.09mL
5mM0.28mL1.41mL2.82mL
10mM0.14mL0.7mL1.41mL
50mM0.03mL0.14mL0.28mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet