PotentandselectiveGPR139agonist(EC50=16nM).SelectiveforGPR139overapanelofGPCRs,ionchannelsandtransporters,includingGPR142.Brainandcellpenetrant.Orallybioavailable.
M.Wt | 316.78 |
Formula | C17H17ClN2O2 |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 1802326-66-4 |
PubChemID | 2548547 |
InChIKey | MWDVCHRYCKXEBY-LBPRGKRZSA-N |
Smiles | O=C(CNC(C1=CC=CC(Cl)=C1)=O)N[C@@H](C)C2=CC=CC=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 31.68 | 100 | |
ethanol | 6.34 | 20 |
Thefollowingdataisbasedontheproductmolecularweight316.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.16mL | 15.78mL | 31.57mL |
5mM | 0.63mL | 3.16mL | 6.31mL |
10mM | 0.32mL | 1.58mL | 3.16mL |
50mM | 0.06mL | 0.32mL | 0.63mL |