PotentandhighlyselectivehistamineH3receptoragonist(pEC50=9.74)thatdisplays300-foldselectivityovertheH4receptor(pKivaluesare9.07and6.61respectively).DoesnotbindtoH1orH2receptorsatconcentrationsupto10μM. .
M.Wt | 321.01 |
Formula | C9H9N3.2HBr |
Storage | DesiccateatRT |
Purity | ≥99%(HPLC) |
CASNumber | 699020-93-4 |
PubChemID | 16759172 |
InChIKey | CYNKWHIKNDIVDR-UHFFFAOYSA-N |
Smiles | Br.Br.C(C1=CN=CN1)C1=CC=NC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
water | 32.1 | 100 |
Thefollowingdataisbasedontheproductmolecularweight321.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.12mL | 15.58mL | 31.15mL |
5mM | 0.62mL | 3.12mL | 6.23mL |
10mM | 0.31mL | 1.56mL | 3.12mL |
50mM | 0.06mL | 0.31mL | 0.62mL |