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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Ibutilide hemifumarate/3908/50/50 mg
产品编号:3908/50
市  场 价:¥2780.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Ibutilide hemifumarate/3908/50/50 mg
商品介绍
Description:BlocksIKr,hERGandL-typeCa2+channels;classIIIantiarrhythmic
ChemicalName:(±)-N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]methanesulfonamidehemifumarate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ClassIIIantiarrhythmic.BlockstherapidcomponentofdelayedrectifierK+current(IKr);alsoblockshERGchannelsandL-typeCa2+channels.ShowntoactivateaslowinwardNa+currentinguineapigventricularcells.Usedtoterminateatrialfibrillationandatrialflutter;canprolongQT.

CompoundLibraries

IbutilidehemifumarateisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt442.61
FormulaC20H36N2O3S.½C4H4O4
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber122647-32-9
PubChemID5281065
InChIKeyPCIOHQNIRPWFMV-WXXKFALUSA-N
SmilesCCCCCCCN(CC)CCCC(O)C1=CC=C(NS(C)(=O)=O)C=C1.O=C(/C=C/C(O)=O)O.CCCCCCCN(CC)CCCC(O)C2=CC=C(NS(C)(=O)=O)C=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO44.26100
ethanol44.26100
water44.26100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight442.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.26mL11.3mL22.59mL
5mM0.45mL2.26mL4.52mL
10mM0.23mL1.13mL2.26mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet