Negativecontrolforendo-IWR1(Cat.No.3532).25-foldlessactivethanendo-IWR1;exhibitsdecreasedactivityagainsttheWnt/β-cateninpathway.
exo-IWR1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 409.44 |
| Formula | C25H19N3O3 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 1127442-87-8 |
| PubChemID | 1163034 |
| InChIKey | ZGSXEXBYLJIOGF-BTYSMDAFSA-N |
| Smiles | O=C(NC5=CC=CC6=C5N=CC=C6)C(C=C4)=CC=C4N2C([C@@]1([H])[C@@H](C3)C=C[C@@H]3[C@]([H])1C2=O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 40.94 | 100 |
Thefollowingdataisbasedontheproductmolecularweight409.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.44mL | 12.21mL | 24.42mL |
| 5mM | 0.49mL | 2.44mL | 4.88mL |
| 10mM | 0.24mL | 1.22mL | 2.44mL |
| 50mM | 0.05mL | 0.24mL | 0.49mL |



