PotentinhibitorofWnt/β-cateninsignaling(IC50=25nM).HasminimaleffectonNotchandHedgehogsignalingpathways.InducesdifferentiationofcardiomyocytesfromhumanESCsandiPSCs.
M.Wt | 496.62 |
Formula | C23H20N4O3S3 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 686772-17-8 |
PubChemID | 2155264 |
InChIKey | RHUJMHOIQBDFQR-UHFFFAOYSA-N |
Smiles | O=C1C3=C(CCS3)N=C(SCC(NC4=NC(C=CC(C)=C5)=C5S4)=O)N1C2=C(OC)C=CC=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 4.97 | 10mMwithsonication |
Thefollowingdataisbasedontheproductmolecularweight496.62.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.01mL | 10.07mL | 20.14mL |
5mM | 0.4mL | 2.01mL | 4.03mL |
10mM | 0.2mL | 1.01mL | 2.01mL |
50mM | 0.04mL | 0.2mL | 0.4mL |