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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ITE/1803/10/10 mg
产品编号:1803/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ITE/1803/10/10 mg
商品介绍
Description:EndogenousagoNISTforthetranscriptionfactorarylhydrocarbonreceptor
AlternativeNames:Arylhydrocarbonreceptorligand
ChemicalName:2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylicacidmethylester
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Endogenousarylhydrocarbonreceptor(AhR)agonist(Ki=3nM).DecreasesOct4levelsinU87glioblastomacells.Inducesstem-likecancercelldifferentiationinU87tumorspheresandinhibitsovariancancercellproliferationinvitro.SuppressestumorgrowthinU87andOVCAR-3cellxenograftsinmice.AlsoinhibitsTGF-β-inducedhumanmyofibroblastdifferentiation.

LicensingInformation

Soldunderlicense,USPatentApplication2002183524

CompoundLibraries

ITEisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt286.3
FormulaC14H10N2O3S
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber448906-42-1
PubChemID4668801
InChIKeyKDDXOGDIPZSCTM-UHFFFAOYSA-N
SmilesCOC(=O)C1=CSC(=N1)C(=O)C1=CNC2=CC=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.63100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight286.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.49mL17.46mL34.93mL
5mM0.7mL3.49mL6.99mL
10mM0.35mL1.75mL3.49mL
50mM0.07mL0.35mL0.7mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet