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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ISX 9/4439/50/50 mg
产品编号:4439/50
市  场 价:¥14180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$709.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ISX 9/4439/50/50 mg
商品介绍
Description:Neurogenicagent;inducesneuronaldifferentiationofSVZProgenitorsandalsoinducescardiomyogenicdifferentiation
ChemicalName:N-Cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Neurogenicagent.MediatesneuroDreportergeneinductionviaactivationofCa2+influx;increasesexpressionofneurogenicdifferentiation1(NeuroD1)transcriptionfactor.Inducesneuronaldifferentiationinhumancorticalneuronalcells(HCN),adultmousewholebrain(MWB)andsubventricularzone(SVZ)progenitors.AlsoshowntoinducecardiomyogenicdifferentiationofNotch-activatedepicardium-derivedcellsinvitro.

CompoundLibraries

ISX9isalsoofferedaspartoftheTocriscreenPlusandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt234.27
FormulaC11H10N2O2S
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber832115-62-5
PubChemID19582717
InChIKeySYENTKHGMVKGAQ-UHFFFAOYSA-N
SmilesO=C(NC2CC2)C1=NOC(C3=CC=CS3)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO23.43100
ethanol11.7150

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight234.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.27mL21.34mL42.69mL
5mM0.85mL4.27mL8.54mL
10mM0.43mL2.13mL4.27mL
50mM0.09mL0.43mL0.85mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet