Neurogenicagent.MediatesneuroDreportergeneinductionviaactivationofCa2+influx;increasesexpressionofneurogenicdifferentiation1(NeuroD1)transcriptionfactor.Inducesneuronaldifferentiationinhumancorticalneuronalcells(HCN),adultmousewholebrain(MWB)andsubventricularzone(SVZ)progenitors.AlsoshowntoinducecardiomyogenicdifferentiationofNotch-activatedepicardium-derivedcellsinvitro.
ISX9isalsoofferedaspartoftheTocriscreenPlusandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight234.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
