Maintainsembryonicstemcell(ESC)pluripotencyinWnt3a-treatedcells;enablesWnt/β-catenin-drivenexpansionofmouseESCsandpreventsspontaneousdifferentiation.UpregulatesexpressionofOct4andSox2transcriptionfactors.Bindstoserine/threoninephosphatasePP2AandpreventsPP2A/Nkdinteraction.
IQ1isalsoofferedaspartoftheTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight362.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.