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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/IP7e/5699/50/50 mg
产品编号:5699/50
市  场 价:¥13300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$665.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/IP7e/5699/50/50 mg
商品介绍
Description:PotentNurr1activator
ChemicalName:6-[4-[(2-Methoxyethoxy)methyl]phenyl]-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-4(5H)-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentNurr1activator(EC50=3.9nM).Delaysonsetandreducesseverityofsymptomsinmicewithexperimentalautoimmuneencephalomyelitis(EAE).AlsosuppressesNF-κBsignaling.Brainpenetrantandorallybioavailable.

TechnicalData

M.Wt390.43
FormulaC23H22N2O4
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber500164-74-9
PubChemID9908426
InChIKeyYCAACZFPADQMAR-UHFFFAOYSA-N
SmilesCN1C(C2=CC=C(COCCOC)C=C2)=CC3=C(C(C4=CC=CC=C4)=NO3)C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO39.04100
ethanol7.8120mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight390.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.56mL12.81mL25.61mL
5mM0.51mL2.56mL5.12mL
10mM0.26mL1.28mL2.56mL
50mM0.05mL0.26mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet