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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/IDE 2/4016/50/50 mg
产品编号:4016/50
市  场 价:¥14180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$709.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/IDE 2/4016/50/50 mg
商品介绍
Description:InducesdefinitiveendodermformationinmouseandhumanESCs
ChemicalName:Heptanedioicacid-1-(2-cyclopentylidenehydrazide)
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Cell-permeableinducerofdefinitiveendodermformationinmouseandhumanembryonicstemcells(ESCs)(EC50=223nMforinductionofSox17expressioninESCs).ReportedtoactivateTGF-βsignalinganddownstreamSmad2phosphorylation;upregulatesNodalexpression.PromotespancreaticProgenitorcellformationinvitro,andguttubeformationinvivo.

LicensingInformation

SoldforresearchpurposeunderlicensefromHarvardUniversity.

TechnicalData

M.Wt240.3
FormulaC12H20N2O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1136466-93-7
PubChemID23836158
InChIKeyCVYPYYPTFNVREL-UHFFFAOYSA-N
SmilesO=C(N/N=C1/CCCC1)CCCCCC(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO24.03100
water4.8120

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight240.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.16mL20.81mL41.61mL
5mM0.83mL4.16mL8.32mL
10mM0.42mL2.08mL4.16mL
50mM0.08mL0.42mL0.83mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet