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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/(R)-2-Hydroxyglutaric acid disodium salt/6124/50/50 mg
产品编号:6124/50
市  场 价:¥1980.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$99.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/(R)-2-Hydroxyglutaric acid disodium salt/6124/50/50 mg
商品介绍
Description:KDM4Ainhibitor;alsoNF-κBactivator
AlternativeNames:D-α-hydroxyglutaricaciddisodiumsalt
ChemicalName:(R)-2-Hydroxypentanedioicaciddisodiumsalt
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Oncometaboliteproducedbymutantisocitratedehydrogenase1(IDH1)andIDH2.InhibitsKDM4AinmurineembryonicfibroblastsresultinginactivationofmTOR.AlsoactivatesNF-κBinbonemarrowstromalcells.

TechnicalData

M.Wt192.08
FormulaC5H6Na2O5
StorageStoreat-20°C
CASNumber103404-90-6
PubChemID45489701
InChIKeyDZHFTEDSQFPDPP-HWYNEVGZSA-L
SmilesO[C@@H](C(O[Na])=O)CCC(O[Na])=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water19.21100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight192.08.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM5.21mL26.03mL52.06mL
5mM1.04mL5.21mL10.41mL
10mM0.52mL2.6mL5.21mL
50mM0.1mL0.52mL1.04mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet