LiverXreceptor(LXR)agonist.Alsoestrogenreceptorpartialagonist.Suppressesβ-estrADIol-mediatedbreastcancercellproliferationinvitro.Alsoincreasesα-synucleinlevelsandinducesapoptosisinhumanneuroblastomacellsinvitro.Endogenouscholesterolmetabolite.
M.Wt | 402.65 |
Formula | C27H46O2 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 20380-11-4 |
PubChemID | 123976 |
InChIKey | FYHRJWMENCALJY-YSQMORBQSA-N |
Smiles | O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC[C@@H](C)CO |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
ethanol | 8.05 | 20 |
Thefollowingdataisbasedontheproductmolecularweight402.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.48mL | 12.42mL | 24.84mL |
5mM | 0.5mL | 2.48mL | 4.97mL |
10mM | 0.25mL | 1.24mL | 2.48mL |
50mM | 0.05mL | 0.25mL | 0.5mL |