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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Harmane/1132/100/100 mg
产品编号:1132/100
市  场 价:¥1300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$65.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Harmane/1132/100/100 mg
商品介绍
Description:Putativeendogenousimidazolineligand.AlsoMAOinhibitor
AlternativeNames:Harman
ChemicalName:1-Methyl-9H-pyrido[3,4-b]indole
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Proposedastheendogenousligandforimidazolinebindingsites.BindstoI1-sitesinratkidney(IC50=31nM)andI2-sites(Ki=49nM).Producesdose-dependenthypotensioninvivothatisreversedbyefaroxan(Cat.No.0792).PotentinhibitorofmonoamineoxidaseAandB(IC50valuesare0.5and5μMrespectively).

TechnicalData

M.Wt182.22
FormulaC12H10N2
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber486-84-0
PubChemID5281404
InChIKeyPSFDQSOCUJVVGF-UHFFFAOYSA-N
SmilesCC1=NC=CC2=C1NC1=C2C=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.HCl1.8210
DMSO21.87100
ethanol21.87100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight182.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM5.49mL27.44mL54.88mL
5mM1.1mL5.49mL10.98mL
10mM0.55mL2.74mL5.49mL
50mM0.11mL0.55mL1.1mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet