Platelet-activatingfactor(PAF)receptorantagonist(Ki=1.3μM).Inhibitsneutrophildegranulationandsuperoxideproductioninvitroandinhibitsbronchoconstrictionandisneuroprotectivefollowingoraladministrationinvivo.
GinkgolideBisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 424.4 |
Formula | C20H24O10 |
Storage | Desiccateat+4°C |
CASNumber | 15291-77-7 |
PubChemID | 10971931 |
InChIKey | SQOJOAFXDQDRGF-OTJOYSMWSA-N |
Smiles | O=C1[C@@H](C)[C@@]2(O)[C@@]([C@H](O)C34[C@]52O[C@@]6([H])[C@]([C@@H](O)C(O6)=O)3[C@H]([C@](C)(C)C)C[C@H]4O[C@]5=O)([H])O1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 42.44 | 100 | |
ethanol | 10.61 | 25 |
Thefollowingdataisbasedontheproductmolecularweight424.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.36mL | 11.78mL | 23.56mL |
5mM | 0.47mL | 2.36mL | 4.71mL |
10mM | 0.24mL | 1.18mL | 2.36mL |
50mM | 0.05mL | 0.24mL | 0.47mL |