Peptidederivedfromconnexin43thatisaselectivegapjunctionblocker.AttenuatesACh-inducedarterialrelaxationandreducesK+-mediatedsmoothmusclerepolarizationinendothelium-intactvesselsinvitro.
M.Wt | 1304.55 |
Formula | C60H101N15O17 |
Sequence | SRPTEKTIFII |
Storage | Desiccateat-20°C |
CASNumber | 198284-64-9 |
PubChemID | 9920128 |
InChIKey | SXRAPDIXXYFGJG-MDAHIHQXSA-N |
Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solubility | Solubleto1mg/mlinwater |
Thefollowingdataisbasedontheproductmolecularweight1304.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 0.77mL | 3.83mL | 7.67mL |
5mM | 0.15mL | 0.77mL | 1.53mL |
10mM | 0.08mL | 0.38mL | 0.77mL |
50mM | 0.02mL | 0.08mL | 0.15mL |