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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Gap 26/1950/1/1 mg
产品编号:1950/1
市  场 价:¥5100.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$255.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Gap 26/1950/1/1 mg
商品介绍
Description:Gapjunctionblocker;inhibitssmoothmusclecontractionandIP3-mediatedATPrelease
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Peptide,correspondingtoresidues63-75ofconnexin43,whichisagapjunctionblocker.Attenuatesrhythmiccontractileactivityofrabbitarterialsmoothmuscle(IC50=28.4μM).AlsoinhibitsIP3-inducedATPrelease,withoutinhibitinggapjunctionalcouplinginendothelialcells.

TechnicalData

M.Wt1550.79
FormulaC70H107N19O19S
SequenceVCYDKSFPISHVR
StorageDesiccateat-20°C
CASNumber197250-15-0
PubChemID25088334
InChIKeyFDPIMWZHGJNESB-VCSXYVMHSA-N
Smiles[H]N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto2mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1550.79.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.64mL3.22mL6.45mL
5mM0.13mL0.64mL1.29mL
10mM0.06mL0.32mL0.64mL
50mM0.01mL0.06mL0.13mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet