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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Galeterone/6108/50/50 mg
产品编号:6108/50
市  场 价:¥11700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$585.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Galeterone/6108/50/50 mg
商品介绍
Description:CYP17inhibitor;alsoandrogenreceptorantagoNIST
AlternativeNames:TOK-001,VN/124-1
ChemicalName:(3β)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CYP17inhibitor(IC50=300nM)andandrogenreceptorantagonist(IC50=384nMinPC3-ARcells).InhibitsDHT-stimulatedprostatecancercellproliferationinvitro.ExhibitsantitumoractivityinSCIDmicebearingprostatecancerxenografts.

TechnicalData

M.Wt388.55
FormulaC26H32N2O
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber851983-85-2
PubChemID11188409
InChIKeyPAFKTGFSEFKSQG-PAASFTFBSA-N
Smiles[H][C@@]12CC=C([C@]1(CC[C@]3([C@]2(CC=C4C[C@H](CC[C@]34C)O)[H])[H])C)N5C=NC6=CC=CC=C56

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO19.4350
ethanol19.4350

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight388.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.57mL12.87mL25.74mL
5mM0.51mL2.57mL5.15mL
10mM0.26mL1.29mL2.57mL
50mM0.05mL0.26mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet