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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/GW 9508/2649/50/50 mg
产品编号:2649/50
市  场 价:¥12580.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$629.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/GW 9508/2649/50/50 mg
商品介绍
Description:PotentandselectiveFFA1(GPR40)agoNIST
ChemicalName:4-[[(3-Phenoxyphenyl)methyl]amino]benzenepropanoicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveagonistforthefreefattyacidreceptorFFA1(GPR40)(pEC50valuesare7.32,<4.3and<4.3forFFA1,FFA2andFFA3receptorsrespectively).InactiveagainstarangeofotherGPCRs,kinases,proteases,integrinsandPPARs.Potentiatesglucose-stimulatedinsulinsecretioninMIN6cells(pEC50=6.14).

LicensingInformation

SoldwiththepermissionofGlaxoSmithKline

CompoundLibraries

GW9508isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt347.41
FormulaC22H21NO3
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber885101-89-3
PubChemID11595431
InChIKeyDGENZVKCTGIDRZ-UHFFFAOYSA-N
SmilesOC(=O)CCC1=CC=C(NCC2=CC=CC(OC3=CC=CC=C3)=C2)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO34.74100
ethanol34.74100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight347.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.88mL14.39mL28.78mL
5mM0.58mL2.88mL5.76mL
10mM0.29mL1.44mL2.88mL
50mM0.06mL0.29mL0.58mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet