KV7(KCNQ)channelactivator(EC50valuesare0.6-100μMforKV7.1-KV7.5).Anticonvulsant.Orallybioavailable.
M.Wt | 303.33 |
Formula | C16H18FN3O2 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 150812-12-7 |
PubChemID | 121892 |
InChIKey | PCOBBVZJEWWZFR-UHFFFAOYSA-N |
Smiles | CCOC(NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 30.33 | 100 | |
ethanol | 30.33 | 100 |
Thefollowingdataisbasedontheproductmolecularweight303.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.3mL | 16.48mL | 32.97mL |
5mM | 0.66mL | 3.3mL | 6.59mL |
10mM | 0.33mL | 1.65mL | 3.3mL |
50mM | 0.07mL | 0.33mL | 0.66mL |