Anticonvulsantandantiepileptic;alsousedtotreatneuropathicpain.Bindswithhighaffinityandselectivitytotheα2δsubunitofvoltage-sensitiveCa2+channelsandmodulatestheiractivity.Displaysanxiolytic-likeactivityinethologicalandconflictmodelsofanxiety.AnalogofGABA(Cat.No.0344).
SoldforresearchpurposesunderagreementfromPfizerInc.
M.Wt | 159.23 |
Formula | C8H17NO2 |
Storage | StoreatRT |
CASNumber | 148553-50-8 |
PubChemID | 5486971 |
InChIKey | AYXYPKUFHZROOJ-ZETCQYMHSA-N |
Smiles | CC(C)C[C@H](CN)CC(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
water | 15.92 | 100 |
Thefollowingdataisbasedontheproductmolecularweight159.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 6.28mL | 31.4mL | 62.8mL |
5mM | 1.26mL | 6.28mL | 12.56mL |
10mM | 0.63mL | 3.14mL | 6.28mL |
50mM | 0.13mL | 0.63mL | 1.26mL |