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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Naloxone benzoylhydrazone/1419/50/50 mg
产品编号:1419/50
市  场 价:¥9700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$485.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Naloxone benzoylhydrazone/1419/50/50 mg
商品介绍
Description:FullκagoNIST,partialμandδagonistandantagonizesagonist-inducedactivationofNOP
AlternativeNames:NalBzOH
ChemicalName:[(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]benzoicacidhydrazide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Mixedopioidreceptoragonist/antagonist.Actsasapotentandfullagonistatκ,apartialagonistatμandδopioidreceptors(pEC50valuesare9.45,8.74and8.61inacAMPassay,9.70,8.59and8.49ina[35S]GTPγSbindingassayrespectively).FailstoexertagonisteffectsatNOPreceptorsandantagonizesagonist-inducedNOPactivation.Stimulatesκ-,μ-andδ-mediatedanalgesiaandblocksNOP-inducedsupraspinalnociception.

TechnicalData

M.Wt445.52
FormulaC26H27N3O4
StorageDesiccateat+4°C
Purity≥99%(HPLC)
CASNumber119630-94-3
PubChemID9601084
InChIKeyAKXCFAYOTIEFOH-XTNAHFASSA-N
SmilesO[C@@]23[C@@]([C@]5([H])/C(CC3)=N/NC(C6=CC=CC=C6)=O)(CC4)C1=C(O5)C(O)=CC=C1C[C@H]2N4CC=C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.2850

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight445.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.24mL11.22mL22.45mL
5mM0.45mL2.24mL4.49mL
10mM0.22mL1.12mL2.24mL
50mM0.04mL0.22mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet