PotentendogenouscannABInoidandvanilloidreceptoragonist,withnoactionatdopaminereceptors.SelectiveforCB1overCB2receptors(Kivaluesare0.25and12μMrespectively),andpotentagonistatTRPV1(VR1)receptors(EC50~50nM).MetabolicallystableandcompetitivelyinhibitsFAAHandanandamidetransport.Hascannabinoidandvanilloidactionsinvivo.
M.Wt | 439.64 |
Formula | C28H41NO3 |
Storage | Desiccateat-20°C |
CASNumber | 199875-69-9 |
PubChemID | 5282105 |
InChIKey | MVVPIAAVGAWJNQ-DOFZRALJSA-N |
Smiles | O=C(NCCC1=CC=C(O)C(O)=C1)CCCC=C/CC=C/C/C=CC/C=CCCCCC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solubility | Solubleinethanol(suppliedpre-dissolvedinanhydrousethanol,5mg/ml) |
Thefollowingdataisbasedontheproductmolecularweight439.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.27mL | 11.37mL | 22.75mL |
5mM | 0.45mL | 2.27mL | 4.55mL |
10mM | 0.23mL | 1.14mL | 2.27mL |
50mM | 0.05mL | 0.23mL | 0.45mL |