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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/(S)-WAY 100135 dihydrochloride/1253/50/50 mg
产品编号:1253/50
市  场 价:¥13300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$665.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/(S)-WAY 100135 dihydrochloride/1253/50/50 mg
商品介绍
Description:Potent,selective5-HT1AantagoNIST
ChemicalName:(S)-N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamidedihydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selective5-HT1Areceptorantagonist(IC50=15nM).Selectiveover5-HT1B,1C,2,α1,α2andD2receptors(IC50>1000nM).Centrallyactiveonsystemicadministration.

LicensingInformation

SoldwiththepermissionofWyeth-AyerstResearch,USPatent4,988,814

TechnicalData

M.Wt468.47
FormulaC24H33N3O2.2HCl
StorageDesiccateat+4°C
Purity≥99%(HPLC)
CASNumber149007-54-5
PubChemID6604839
InChIKeyNYZFUZCCDOSQBG-AWEZNQCLSA-N
SmilesO=C(NC(C)(C)C)[C@@]([C@]3=CC=CC=C3)([H])CN(CC2)CCN2C1=C(OC)C=CC=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO46.85100
water2.345mMwithgentlewarming
water4.6810mMwithsonication

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight468.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.13mL10.67mL21.35mL
5mM0.43mL2.13mL4.27mL
10mM0.21mL1.07mL2.13mL
50mM0.04mL0.21mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet