β-adrenoceptorand5-HT1A/1Breceptorantagonist.pKB/pA2valuesare8.3and8.0for5-HT1Aand5-HT1Breceptorsrespectively.Centrallyactivefollowingsystemicadministrationinvivo.
M.Wt | 348.44 |
Formula | C19H28N2O4 |
Storage | StoreatRT |
CASNumber | 39731-05-0 |
PubChemID | 193949 |
InChIKey | SJYFDORQYYEJLB-UHFFFAOYSA-N |
Smiles | CC(C)OC(=O)C1=CC2=C(OCC(O)CNC(C)(C)C)C=CC=C2N1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 34.84 | 100 | |
ethanol | 34.84 | 100 |
Thefollowingdataisbasedontheproductmolecularweight348.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.87mL | 14.35mL | 28.7mL |
5mM | 0.57mL | 2.87mL | 5.74mL |
10mM | 0.29mL | 1.43mL | 2.87mL |
50mM | 0.06mL | 0.29mL | 0.57mL |