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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/GSK LSD 1 dihydrochloride/5361/50/50 mg
产品编号:5361/50
市  场 价:¥13700.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$685.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/GSK LSD 1 dihydrochloride/5361/50/50 mg
商品介绍
Description:PotentandselectiveLSD1inhibitor
ChemicalName:rel-N-[(1S,2R)-2-Phenylcyclopropyl]-4-piperidinaminedihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivelysinespecificdemethylase1(LSD1)inhibitor(IC50=16nM).Exhibits>1000-foldselectivityforLSD1overcloselyrelatedenzymesincludingLSD2,MAO-1andMAO-B.Inhibitscancercelllinegrowthinvitro.

LicensingInformation

ThisprobeissuppliedinconjunctionwiththeStructuralGenomicsConsortium.Forfurthercharacterizationdetails,pleasevisittheGSKLSD1probesummaryontheSGCwebsite.

CompoundLibraries

GSKLSD1dihydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt289.24
FormulaC14H20N2.2HCl
StorageStoreat+4°C
Purity≥98%(HPLC)
PubChemID91663353
InChIKeyPJFZOGMSPBHPNS-WICJZZOFSA-N
SmilesC1(N[C@@H]2C[C@H]2[C@]3=CC=CC=C3)CCNCC1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.92100
water28.92100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight289.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.46mL17.29mL34.57mL
5mM0.69mL3.46mL6.91mL
10mM0.35mL1.73mL3.46mL
50mM0.07mL0.35mL0.69mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet