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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/GS 39783/2001/10/10 mg
产品编号:2001/10
市  场 价:¥2980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$149.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/GS 39783/2001/10/10 mg
商品介绍
Description:PositivemodulatoratGABABreceptors
ChemicalName:N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PositiveallostericmodulatorofGABABreceptorfunction.PotentiatestheeffectsofGABAon[35S]GTPγSbindingatrecombinantandnativeGABABreceptors(EC50valuesare2.1and3.1μMrespectively).Decreasescocaineself-admiNISTration,blockstherewardingpropertiesofnicotineandproducesanxiolytic-likeactivitywithoutthesideeffectsassociatedwithbaclofenorbenzodiazepines.

TechnicalData

M.Wt337.44
FormulaC15H23N5O2S
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber39069-52-8
PubChemID6604928
InChIKeyGSGVDKOCBKBMGG-UHFFFAOYSA-N
SmilesCSC1=NC(NC2CCCC2)=C(C(NC2CCCC2)=N1)[N+]([O-])=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO3.3710
ethanol1.695

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight337.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.96mL14.82mL29.63mL
5mM0.59mL2.96mL5.93mL
10mM0.3mL1.48mL2.96mL
50mM0.06mL0.3mL0.59mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet