GPBAreceptoragonist.UpregulatesGLP-1secretionfromintestinalcultures.IncreasesMQAE-fluorescencesuggestingadecreaseinintracellularchlorideconcentrationingallbladderepithelialcells.
GPBAR-AisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 484.37 |
Formula | C23H15F7N2O2 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 877052-79-4 |
PubChemID | 11656002 |
InChIKey | ZIXNJVGTAXRKAP-UHFFFAOYSA-N |
Smiles | O=C(CO3)N(CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)CC1=C3N=CC=C1C2=C(F)C=CC=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 48.44 | 100 | |
ethanol | 9.69 | 20 |
Thefollowingdataisbasedontheproductmolecularweight484.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.06mL | 10.32mL | 20.65mL |
5mM | 0.41mL | 2.06mL | 4.13mL |
10mM | 0.21mL | 1.03mL | 2.06mL |
50mM | 0.04mL | 0.21mL | 0.41mL |